There is five different endings for Vampire: The Masquerade - Bloodlines. In the endings where Smiling Jack plants C4 in the sarcophagus it is unknown if the Protagonists survives, but looking at the cutscene, it is presumably he/she did not survive the blast.
It's one of the most criticized endings of the game for obvious reasons, and most believe it was the designers first hack at a 'Twist/suprise' kind of ending. Hope this answered your question.
Seeing the cutscene, he/she move away, leaving the prince with the sarcophagus, then he/she have taken for sure the elevator for coming down, and considering a matter of minutes beforeLacroix open the sarcophagus and the explosion blow all, I think that he/she is came at the street level, then in a matter of seconds he/she can take the door and jump in the sewers or exit from the main door.
I want remember to alls that the tower explode only at the top, not totally.