This glassy stone appears to have a liquid core. The stone itself is milky translucent, rock solid, and unlike anything you've seen. Possession of the Heart of Eliza conveys a Melee bonus of one.
― In-game Description
The Heart of Eliza is an occult item in Vampire: The Masquerade – Bloodlines.
It is purchased from Tseng's store in Chinatown. In the Plus Patch it is also possible to get this as a reward from a quest provided by Mr. Ox.
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